Glutamine: An essential ally for the performance and health of athletes
Description : Glutamine: Boost your recovery, immunity, and gut health. A key amino acid for performance, avoiding fatigue, and protecting your muscle mass.

Table of Contents
Glutamine is one of the most studied semi-essential amino acids in the world of sports. Present in abundance in muscles, it plays an essential role in recovery, preservation of muscle mass, intestinal balance and the proper functioning of the immune system . But what are its concrete benefits? Who is glutamine supplementation for? ? What are the signs of a deficit? Dive into this comprehensive article to understand everything about this key amino acid, a true pillar of a healthy lifestyle, whether you're an amateur or a seasoned athlete.
What is glutamine?
Glutamine is a semi-essential amino acid . This means that in most situations, the body can produce enough of it from other amino acids. But under certain conditions – intense exercise, illness, injury, stress – the need increases and endogenous production is no longer sufficient: it then becomes necessary to provide more via food or glutamine supplementation.
Key points:
-Glutamine is the most abundant amino acid in skeletal muscle , representing approximately 60 % of total muscle amino acid stock. [1]
-Its massive presence in muscle tissue makes it a central player in protein synthesis and recovery.
Impulse Nutrition Tip : By favoring a glutamine of plant origin resulting from natural fermentation, we optimize purity while guaranteeing rapid and effective absorption.
The role of glutamine in the body
Glutamine performs many essential functions : [2]
-Protein synthesis : Glutamine is an important amino acid in protein synthesis, which helps build and maintain muscle mass. It serves as a substrate for protein production in muscles.
-Energy source: Glutamine is a key energy source for some cells, including immune cells (lymphocytes, macrophages) and intestinal cells (enterocytes). These cells use glutamine as their primary fuel.
-Intestinal balance: Glutamine contributes to the integrity of the intestinal mucosa, strengthens the intestinal barrier and promotes the regeneration of intestinal cells, which is essential for digestive health.
-Immune system: immune cells use glutamine to function optimally, making it an ally of the immune system, particularly during periods of fatigue or intensive training.
-Acid-base balance and blood circulation: glutamine plays a role in pH regulation and the elimination of nitrogenous waste.
This versatility explains why glutamine is often recommended for athletes seeking performance and accelerated recovery.
Glutamine and athletic performance: what does the science say?
An amino acid for recovery and performance
Taking glutamine promotes better recovery after intense exercise. It limits the decline in intramuscular glutamine levels, a factor directly associated with muscle fatigue and loss of performance.
Concrete effects of glutamine supplementation in athletes:
-Reduction of muscle catabolism: Glutamine limits protein breakdown during phases of intense stress (training, injury or illness).
-Optimization of muscle recovery: By promoting protein synthesis and cell proliferation, glutamine accelerates the repair of damaged muscle fibers.
-Support of immune function: During prolonged or intense exercise, the immune system is weakened. Glutamine, the preferred fuel of lymphocytes, helps strengthen immune defenses and reduces the risk of post-exercise infections.
-Contribution to intestinal well-being: By improving intestinal permeability and supporting the mucosal barrier, glutamine optimizes the absorption of nutrients essential for performance and recovery.
Specific applications according to the type of sport
-Endurance sports: Glutamine helps limit muscle fatigue, preserves muscle integrity and supports the immune system, essential during prolonged efforts.
- Bodybuilding: It promotes mass gain by reducing catabolism and accelerates recovery, allowing more frequent and intensive training.
-Sports involving repeated short and intense efforts such as crossfit, HIIT or team sports: By supporting rapid recovery and strengthening immune resistance, glutamine helps optimize performance during demanding and repeated sessions.
Signs of glutamine deficiency
In healthy, resting individuals, glutamine deficiency is rare because the body can synthesize enough of it, especially under normal conditions.
During high metabolic stress (prolonged exercise, close competition, injuries, infections), glutamine demand increases sharply, potentially leading to a decline in muscle stores —sometimes referred to as a “conditional glutamine state.”
Symptoms suggestive of glutamine deficiency:
-Persistent fatigue, drop in physical performance.
-Slowed muscle recovery.
-Increased sensitivity to infections (colds, digestive disorders, etc.).
-Digestive disorders: discomfort, intestinal permeability, digestive problems.
-Muscle wasting, difficulty maintaining or developing muscle mass.
Particular attention should be paid to athletes gaining mass or subjected to a very high training volume, as well as to people following restrictive diets (vegetarians, vegans, low-protein diets, etc.).
When and how to supplement glutamine?
Glutamine supplementation may be considered in several situations:
-During periods of intensive preparation (competition, mass gain, high loads), when glutamine needs exceed the endogenous synthesis capacity.
-To support muscle recovery during overexertion.
-In athletes with digestive disorders or a fragile intestinal wall.
-To compensate for insufficient dietary intake in people following special diets, such as vegetarian, vegan or those limiting animal products.
Recommended daily dose
The recommended daily dose generally varies between 3 and 10 g per day, to be adjusted according to the intensity of training and individual needs. For optimal absorption, it is recommended to take it outside of meals (for example, immediately after training or before bedtime), using a measuring spoon.
Impulse Nutrition Tip: To maximize the effects on recovery and immunity, take glutamine away from main meals, in a protein drink or simply diluted in water.
Natural glutamine vs. dietary supplement
Glutamine is found in many amino acid foods, including:
-Food sources rich in glutamine : meat, fish, eggs, dairy products, legumes, certain vegetables (cabbage, spinach).
-But during intensive training, the portion provided by food may prove insufficient to compensate for losses and support recovery.
L-Glutamine Food Supplement: A Precision Choice
BioKyowa® Glutamine is a premium quality glutamine obtained by plant fermentation, without contaminants or chemical solvents, which ensures optimal purity.
Comparative
Classic diet | Impulse Nutrition L-Glutamine Food Supplement |
---|---|
Glutamine present in low quantity, slower absorption | Pure glutamine, fast absorption, guaranteed content |
Variable source depending on food quality | Standardized, traceability, adapted to specific diets (vegetarians, athletes) |
Is glutamine useful for all athletes?
Glutamine is particularly recommended:
-In endurance athletes (running, triathlon, cycling) who draw heavily on their amino acid reserves.
-In bodybuilding and strength sports to support protein synthesis and mass gain.
-In people who practice sports involving repeated or high-intensity efforts.
-For those who wish to preserve their intestinal health and strengthen their barrier function.
Please note: glutamine is suitable for both men and women. The only restriction: glutamine supplementation is not recommended for pregnant and breastfeeding women without medical advice.
Conclusion: Glutamine, an essential lever for athletic progress
Glutamine is not just an amino acid: it is a real performance lever, which acts on recovery, immunity, intestinal health and the maintenance of muscle mass. Through its many functions, it supports each athlete towards the expression of their full potential. Choosing a high-quality glutamine, derived from plant sources and rigorously controlled, is choosing safety, performance and lasting well-being.
See the product in our store and make glutamine your daily ally.
SOURCES
[ 1] Cruzat VF “ Glutamine and Skeletal Muscle ”. In: Nutr . Skeletal . Muscle [Online]. [ sl .]: Elsevier, 2019. p. 299 - 313. Available on : < https://doi.org/10.1016/B978-0-12-810422-4.00017-8 > (accessed June 6, 2025) ISBN : 978-0-12-810422-4.
[2] Coqueiro AY, Rogero MM, Tirapegui J. “ Glutamine as an Anti-Fatigue Amino Acid in Sports Nutrition ”. Nutrients [Online]. April 2019. Vol. 11, n°4, p. 863. Available on : < https://doi.org/10.3390/nu11040863 >